Search results for "genome-scale metabolic modeling"

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Integrative Gene Expression and Metabolic Analysis Tool IgemRNA

2022

ABSTRACTGenome scale metabolic modelling is widely used technique to research metabolism impacts on organism’s properties. Additional omics data integration enables a more precise genotype-phenotype analysis for biotechnology, medicine and life sciences. Transcriptome data amounts rapidly increase each year. Many transcriptome analysis tools with integrated genome scale metabolic modelling are proposed. But these tools have own restrictions, compatibility issues and the necessity of previous experience and advanced user skills. We have analysed and classified published tools, summarized possible transcriptome pre-processing, and analysis methods and implemented them in the new transcriptome…

business.industryComputer scienceProcess (engineering)Metabolic networkData validationComputational biologyBiochemistryToolboxTranscriptomeSoftwaregenome-scale metabolic modeling; transcriptomics; software engineering; Cobra Toolbox 3.0; MATLAB; flux balance analysis; flux variability analysis; omics data analysisbusinessFlux (metabolism)Molecular BiologyGraphical user interfaceBiomolecules; Volume 12; Issue 4; Pages: 586
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